Precision TMS

Neuroimaging-Informed, Personalized Transcranial Magnetic Stimulation Targeting

Applications > Precison TMS

Standard TMS targets by convention, without confirming whether a region is dysregulated or how.

LucerumCarto aggregates quantitative EEG into normative deviations in source-space current density, connectomic dysregulation, and network-level discriminants, making clinical patterns visible before any treatment decision is made.

Two paths to locate the best target

  • Brain source activity — A brain map from patient’s qEEG or fMRI identifies the region of interest directly. Start here when the source of abnormal activity is cortically accessible.

  • Unique Navigation by Connectivity — Select a symptom-relevant network or deep node. LucerumCarto resolves the cortical region most strongly connected to it, applying the same logic behind sgACC–DLPFC targeting in depression — yet available for any dysregulated node or condition.

UNDERSTAND THE DYSREGULATION BEFORE YOU STIMULATE

  • Source-space deviation from qEEG or fMRI

  • Connectivity profile (correlated/anticorrelated)

  • Network participation and hub status

  • Frequency and phase features

Reachability is computed based on your coil’s field

Every candidate region — whether a direct cortical source or a surface proxy for a deeper node — is evaluated against the coil's depth–focality tradeoff and modeled for the best achievable induced E-field, within established superficial-exposure safety limits. If a target cannot be adequately stimulated from directly above it, LucerumCarto tells you before the session begins.

Optimize for both field and dysregulation

When the coil position directly above a target cannot deliver optimal field strength due to orientation, LucerumCarto's algorithms jointly maximize the effective E-field at the best achievable tangential coil orientation and the location of dysregulation.

The result is the coil position that delivers both the strongest feasible clinically relevant dose and the maximal engagement with the dysregulated tissue.

Export-Ready Protocols

  • A built-in interactive wizard leads to structured rTMS protocols ready for export.

  • The LucerumCarto team also supports direct integration with your TMS machine for a seamless clinical workflow.

The future of precision neuromodulation